Target Gene Table ▼
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10013412HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013413HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013414HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013415HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013416HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013417HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013418HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013419HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013420HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10019801HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options ▼
Drug Information ▼
GeneCHRM3
DrugBank IDDB00193
Drug NameTramadol
Target IDBE0000045
UniProt IDP20309
Regulation Typeantagonist
PubMed IDs11561087; 12401609; 31004280
CitationsShiraishi M, Minami K, Uezono Y, Yanagihara N, Shigematsu A: Inhibition by tramadol of muscarinic receptor-induced responses in cultured adrenal medullary cells and in Xenopus laevis oocytes expressing cloned M1 receptors. J Pharmacol Exp Ther. 2001 Oct;299(1):255-60.@@Shiga Y, Minami K, Shiraishi M, Uezono Y, Murasaki O, Kaibara M, Shigematsu A: The inhibitory effects of tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M(3) receptors. Anesth Analg. 2002 Nov;95(5):1269-73, table of contents.@@Barakat A: Revisiting Tramadol: A Multi-Modal Agent for Pain Management. CNS Drugs. 2019 May;33(5):481-501. doi: 10.1007/s40263-019-00623-5.
GroupsApproved; Investigational
Direct Classification
SMILESCOC1=CC=CC(=C1)C1(O)CCCCC1CN(C)C
PathwaysTramadol Metabolism Pathway; Tramadol Action Action Pathway
PharmGKBPA451735
ChEMBLCHEMBL1237044