| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006400 | HBV | ENSG00000006071.16 | protein_coding | ABCC8 | No | No | 6833 | Q09428 |
| TVIS10014476 | HBV | ENSG00000006071.16 | protein_coding | ABCC8 | No | No | 6833 | Q09428 |
| TVIS20010586 | HPV | ENSG00000006071.16 | protein_coding | ABCC8 | No | No | 6833 | Q09428 |
| TVIS44004571 | HTLV-1 | ENSG00000006071.16 | protein_coding | ABCC8 | No | No | 6833 | Q09428 |
| TVIS44020396 | HTLV-1 | ENSG00000006071.16 | protein_coding | ABCC8 | No | No | 6833 | Q09428 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABCC8 |
|---|---|
| DrugBank ID | DB01382 |
| Drug Name | Glymidine |
| Target ID | BE0000207 |
| UniProt ID | Q09428 |
| Regulation Type | inducer |
| PubMed IDs | 12031979; 12107069; 12145099; 12213059; 12213829; 9990013 |
| Citations | Dabrowski M, Ashcroft FM, Ashfield R, Lebrun P, Pirotte B, Egebjerg J, Bondo Hansen J, Wahl P: The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener. Diabetes. 2002 Jun;51(6):1896-906.@@Hambrock A, Preisig-Muller R, Russ U, Piehl A, Hanley PJ, Ray J, Daut J, Quast U, Derst C: Four novel splice variants of sulfonylurea receptor 1. Am J Physiol Cell Physiol. 2002 Aug;283(2):C587-98.@@Hambrock A, Loffler-Walz C, Quast U: Glibenclamide binding to sulphonylurea receptor subtypes: dependence on adenine nucleotides. Br J Pharmacol. 2002 Aug;136(7):995-1004.@@Nielsen FE, Bodvarsdottir TB, Worsaae A, MacKay P, Stidsen CE, Boonen HC, Pridal L, Arkhammar PO, Wahl P, Ynddal L, Junager F, Dragsted N, Tagmose TM, Mogensen JP, Koch A, Treppendahl SP, Hansen JB: 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells. J Med Chem. 2002 Sep 12;45(19):4171-87.@@Babenko AP, Bryan J: SUR-dependent modulation of KATP channels by an N-terminal KIR6.2 peptide. Defining intersubunit gating interactions. J Biol Chem. 2002 Nov 15;277(46):43997-4004. Epub 2002 Sep 3.@@Ueda K, Komine J, Matsuo M, Seino S, Amachi T: Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1268-72. |
| Groups | Approved; Investigational |
| Direct Classification | Benzenesulfonamides |
| SMILES | COCCOC1=CN=C(NS(=O)(=O)C2=CC=CC=C2)N=C1 |
| Pathways | |
| PharmGKB | PA164748839 |
| ChEMBL | CHEMBL1697838 |
