| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30078583 | HIV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20009148 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20009386 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS20059821 | HPV | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
| TVIS44038999 | HTLV-1 | ENSG00000113749.8 | protein_coding | HRH2 | No | No | 3274 | A0A1B0GTK7 P25021 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HRH2 |
|---|---|
| DrugBank ID | DB00972 |
| Drug Name | Azelastine |
| Target ID | BE0000112 |
| UniProt ID | P25021 |
| Regulation Type | inhibitor |
| PubMed IDs | 17723160; 20856595; 19209282 |
| Citations | Bernstein JA: Azelastine hydrochloride: a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability. Curr Med Res Opin. 2007 Oct;23(10):2441-52.@@Williams PB, Crandall E, Sheppard JD: Azelastine hydrochloride, a dual-acting anti-inflammatory ophthalmic solution, for treatment of allergic conjunctivitis. Clin Ophthalmol. 2010 Sep 7;4:993-1001. doi: 10.2147/opth.s13479.@@Horak F: Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis. Ther Clin Risk Manag. 2008 Oct;4(5):1009-22. |
| Groups | Approved |
| Direct Classification | Phthalazinones |
| SMILES | CN1CCCC(CC1)N1N=C(CC2=CC=C(Cl)C=C2)C2=CC=CC=C2C1=O |
| Pathways | Azelastine H1-Antihistamine Action |
| PharmGKB | PA448517 |
| ChEMBL | CHEMBL639 |
