Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30078583HIVENSG00000113749.8protein_codingHRH2NoNo3274A0A1B0GTK7
P25021
TVIS20009148HPVENSG00000113749.8protein_codingHRH2NoNo3274A0A1B0GTK7
P25021
TVIS20009386HPVENSG00000113749.8protein_codingHRH2NoNo3274A0A1B0GTK7
P25021
TVIS20059821HPVENSG00000113749.8protein_codingHRH2NoNo3274A0A1B0GTK7
P25021
TVIS44038999HTLV-1ENSG00000113749.8protein_codingHRH2NoNo3274A0A1B0GTK7
P25021
TCGA Plot Options
Drug Information
GeneHRH2
DrugBank IDDB05381
Drug NameHistamine
Target IDBE0000112
UniProt IDP25021
Regulation Typeagonist
PubMed IDs17334413; 17359382; 11752352
CitationsFrancis H, Franchitto A, Ueno Y, Glaser S, DeMorrow S, Venter J, Gaudio E, Alvaro D, Fava G, Marzioni M, Vaculin B, Alpini G: H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway. Lab Invest. 2007 May;87(5):473-87. Epub 2007 Mar 5.@@Soga F, Katoh N, Kishimoto S: Histamine prevents apoptosis in human monocytes. Clin Exp Allergy. 2007 Mar;37(3):323-30.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.
GroupsApproved; Investigational
Direct Classification2-arylethylamines
SMILESNCCC1=CNC=N1
Pathways
PharmGKBPA449880
ChEMBLCHEMBL90