| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30038735 | HIV | ENSG00000169032.11 | protein_coding | MAP2K1 | Yes | No | 5604 | A4QPA9 B4DFY5 Q02750 |
| TVIS20018682 | HPV | ENSG00000169032.11 | protein_coding | MAP2K1 | Yes | No | 5604 | A4QPA9 B4DFY5 Q02750 |
| TVIS20034843 | HPV | ENSG00000169032.11 | protein_coding | MAP2K1 | Yes | No | 5604 | A4QPA9 B4DFY5 Q02750 |
| TVIS44012427 | HTLV-1 | ENSG00000169032.11 | protein_coding | MAP2K1 | Yes | No | 5604 | A4QPA9 B4DFY5 Q02750 |
| TVIS44023718 | HTLV-1 | ENSG00000169032.11 | protein_coding | MAP2K1 | Yes | No | 5604 | A4QPA9 B4DFY5 Q02750 |
| TVIS44051116 | HTLV-1 | ENSG00000169032.11 | protein_coding | MAP2K1 | Yes | No | 5604 | A4QPA9 B4DFY5 Q02750 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAP2K1 |
|---|---|
| DrugBank ID | DB14904 |
| Drug Name | Pimasertib |
| Target ID | BE0010124 |
| UniProt ID | O14733 |
| Regulation Type | inhibitor |
| PubMed IDs | 30585255 |
| Citations | de Weger VA, de Jonge M, Langenberg MHG, Schellens JHM, Lolkema M, Varga A, Demers B, Thomas K, Hsu K, Tuffal G, Goodstal S, Mace S, Deutsch E: A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours. Br J Cancer. 2019 Feb;120(3):286-293. doi: 10.1038/s41416-018-0355-8. Epub 2018 Dec 26. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | OC[C@@H](O)CNC(=O)C1=C(NC2=C(F)C=C(I)C=C2)C=NC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2107832 |
