| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30082247 | HIV | ENSG00000104267.10 | protein_coding | CA2 | No | No | 760 | P00918 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CA2 |
|---|---|
| DrugBank ID | DB00880 |
| Drug Name | Chlorothiazide |
| Target ID | BE0000322 |
| UniProt ID | P00918 |
| Regulation Type | inhibitor |
| PubMed IDs | 14656370; 10954127; 12388412; 11752352 |
| Citations | Weiner ID, Verlander JW: Renal and hepatic expression of the ammonium transporter proteins, Rh B Glycoprotein and Rh C Glycoprotein. Acta Physiol Scand. 2003 Dec;179(4):331-8.@@Puscas I, Coltau M, Baican M, Pasca R, Domuta G: The inhibitory effect of diuretics on carbonic anhydrases. Res Commun Mol Pathol Pharmacol. 1999;105(3):213-36.@@Verlander JW, Miller RT, Frank AE, Royaux IE, Kim YH, Weiner ID: Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney. Am J Physiol Renal Physiol. 2003 Feb;284(2):F323-37. Epub 2002 Oct 8.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Vet_approved |
| Direct Classification | 1,2,4-benzothiadiazine-1,1-dioxides |
| SMILES | NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1 |
| Pathways | Chlorothiazide Action Pathway |
| PharmGKB | PA448953 |
| ChEMBL | CHEMBL842 |
