| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20032009 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44018687 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44018688 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44003389 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44018689 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44009683 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44012424 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44013628 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44033913 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44033910 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE4B |
|---|---|
| DrugBank ID | DB03606 |
| Drug Name | (S)-Rolipram |
| Target ID | BE0000487 |
| UniProt ID | Q07343 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 10592235; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Experimental |
| Direct Classification | Phenylpyrrolidines |
| SMILES | [H][C@@]1(CNC(=O)C1)C1=CC=C(OC)C(OC2CCCC2)=C1 |
| Pathways | |
| PharmGKB | PA153906323 |
| ChEMBL | CHEMBL325795 |
