| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20032009 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44018687 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44018688 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44003389 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44018689 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44009683 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44012424 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44013628 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44033913 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS44033910 | HTLV-1 | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE4B |
|---|---|
| DrugBank ID | DB05266 |
| Drug Name | Ibudilast |
| Target ID | BE0000487 |
| UniProt ID | Q07343 |
| Regulation Type | inhibitor |
| PubMed IDs | 16313925 |
| Citations | Huang Z, Liu S, Zhang L, Salem M, Greig GM, Chan CC, Natsumeda Y, Noguchi K: Preferential inhibition of human phosphodiesterase 4 by ibudilast. Life Sci. 2006 May 1;78(23):2663-8. Epub 2005 Nov 28. |
| Groups | Investigational |
| Direct Classification | Pyrazolopyridines |
| SMILES | CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C |
| Pathways | |
| PharmGKB | PA165958351 |
| ChEMBL | CHEMBL19449 |
