Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30014934HIVENSG00000172819.17protein_codingRARGNoNo5916A8K3H3
P13631
TVIS20027439HPVENSG00000172819.17protein_codingRARGNoNo5916A8K3H3
P13631
TVIS20020554HPVENSG00000172819.17protein_codingRARGNoNo5916A8K3H3
P13631
TVIS44023408HTLV-1ENSG00000172819.17protein_codingRARGNoNo5916A8K3H3
P13631
TCGA Plot Options
Drug Information
GeneRARG
DrugBank IDDB12808
Drug NameTrifarotene
Target IDBE0000144
UniProt IDP13631
Regulation Typeagonist
PubMed IDs29974453
CitationsAubert J, Piwnica D, Bertino B, Blanchet-Rethore S, Carlavan I, Deret S, Dreno B, Gamboa B, Jomard A, Luzy AP, Mauvais P, Mounier C, Pascau J, Pelisson I, Portal T, Rivier M, Rossio P, Thoreau E, Vial E, Voegel JJ: Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-gamma agonist trifarotene. Br J Dermatol. 2018 Aug;179(2):442-456. doi: 10.1111/bjd.16719. Epub 2018 Jul 4.
GroupsApproved; Investigational
Direct ClassificationM-terphenyls
SMILESCC(C)(C)C1=CC(=CC=C1N1CCCC1)C1=CC(=CC=C1OCCO)C1=CC=C(C=C1)C(O)=O
Pathways
PharmGKB
ChEMBLCHEMBL3707313