| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20061995 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20031176 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20065987 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20061884 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20061827 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20062072 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20038159 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20068307 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20061404 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS20016969 | HPV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AHR |
|---|---|
| DrugBank ID | DB12379 |
| Drug Name | Indirubin |
| Target ID | BE0003721 |
| UniProt ID | P35869 |
| Regulation Type | agonist |
| PubMed IDs | 15056799; 25329374 |
| Citations | Adachi J, Mori Y, Matsui S, Matsuda T: Comparison of gene expression patterns between 2,3,7,8-tetrachlorodibenzo-p-dioxin and a natural arylhydrocarbon receptor ligand, indirubin. Toxicol Sci. 2004 Jul;80(1):161-9. Epub 2004 Mar 31.@@Perkins A, Phillips JL, Kerkvliet NI, Tanguay RL, Perdew GH, Kolluri SK, Bisson WH: A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain. Biology (Basel). 2014 Oct 17;3(4):645-69. doi: 10.3390/biology3040645. |
| Groups | Investigational |
| Direct Classification | Indolines |
| SMILES | O=C1NC2=C(C=CC=C2)C1=C1/NC2=C(C=CC=C2)C1=O |
| Pathways | |
| PharmGKB | |
| ChEMBL |
