| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009794 | HBV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS10036366 | HBV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058841 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058842 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058843 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058844 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058845 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058846 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058847 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
| TVIS30058848 | HIV | ENSG00000114200.10 | protein_coding | BCHE | No | No | 590 | P06276 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | BCHE |
|---|---|
| DrugBank ID | DB00382 |
| Drug Name | Tacrine |
| Target ID | BE0002180 |
| UniProt ID | P06276 |
| Regulation Type | inhibitor |
| PubMed IDs | 10375753; 17218977; 12871155; 16860785 |
| Citations | Wang H, Tang XC: Anticholinesterase effects of huperzine A, E2020, and tacrine in rats. Zhongguo Yao Li Xue Bao. 1998 Jan;19(1):27-30.@@Krustev AD, Argirova MD, Getova DP, Turiiski VI, Prissadova NA: Calcium-independent tacrine-induced relaxation of rat gastric corpus smooth muscles. Can J Physiol Pharmacol. 2006 Nov;84(11):1133-8.@@Marco JL, Carreiras MC: Recent developments in the synthesis of acetylcholinesterase inhibitors. Mini Rev Med Chem. 2003 Sep;3(6):518-24.@@Ahmed M, Rocha JB, Correa M, Mazzanti CM, Zanin RF, Morsch AL, Morsch VM, Schetinger MR: Inhibition of two different cholinesterases by tacrine. Chem Biol Interact. 2006 Aug 25;162(2):165-71. Epub 2006 Jun 17. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Acridines |
| SMILES | NC1=C2CCCCC2=NC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA451576 |
| ChEMBL | CHEMBL95 |
