Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10009794HBVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS10036366HBVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058841HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058842HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058843HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058844HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058845HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058846HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058847HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TVIS30058848HIVENSG00000114200.10protein_codingBCHENoNo590P06276
TCGA Plot Options
Drug Information
GeneBCHE
DrugBank IDDB00674
Drug NameGalantamine
Target IDBE0002180
UniProt IDP06276
Regulation Typeinhibitor
PubMed IDs17159811; 11888344; 19811027; 12177686
CitationsSvoboda Z, Kvetina J, Kunesova G, Herink J, Bajgar J, Bartosova L, Zivny P, Palicka V: Effect of galantamine on acetylcholinesterase and butyrylcholinesterase activities in the presence of L-carnitine in rat selected brain and peripheral tissues. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:183-6.@@Giacobini E: Selective inhibitors of butyrylcholinesterase: a valid alternative for therapy of Alzheimer's disease? Drugs Aging. 2001;18(12):891-8.@@Wilkinson DG: Galantamine: a new treatment for Alzheimer's disease. Expert Rev Neurother. 2001 Nov;1(2):153-9. doi: 10.1586/14737175.1.2.153.@@Lilienfeld S: Galantamine--a novel cholinergic drug with a unique dual mode of action for the treatment of patients with Alzheimer's disease. CNS Drug Rev. 2002 Summer;8(2):159-76.
GroupsApproved
Direct ClassificationGalanthamine-type amaryllidaceae alkaloids
SMILES[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3
Pathways
PharmGKBPA449726
ChEMBLCHEMBL659