Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1C |
|---|---|
| DrugBank ID | DB00252 |
| Drug Name | Phenytoin |
| Target ID | BE0008715 |
| UniProt ID | O00555 |
| Regulation Type | inhibitor |
| PubMed IDs | 28349209 |
| Citations | Keppel Hesselink JM: Phenytoin: a step by step insight into its multiple mechanisms of action-80 years of mechanistic studies in neuropharmacology. J Neurol. 2017 Sep;264(9):2043-2047. doi: 10.1007/s00415-017-8465-4. Epub 2017 Mar 27. |
| Groups | Approved; Vet_approved |
| Direct Classification | Phenylhydantoins |
| SMILES | O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| Pathways | Fosphenytoin (Antiarrhythmic) Action Pathway; Fosphenytoin (Antiarrhythmic) Metabolism Pathway; Phenytoin (Antiarrhythmic) Action Pathway |
| PharmGKB | PA450947 |
| ChEMBL | CHEMBL16 |
