VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS10013568 | HBV | ENSG00000151617.17 | protein_coding | EDNRA | No | No | 1909 | P25101 |
TVIS20026127 | HPV | ENSG00000151617.17 | protein_coding | EDNRA | No | No | 1909 | P25101 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | EDNRA |
---|---|
DrugBank ID | DB00945 |
Drug Name | Acetylsalicylic acid |
Target ID | BE0000521 |
UniProt ID | P25101 |
Regulation Type | inhibitor |
PubMed IDs | 10727528; 11093786; 26956245 |
Citations | Talbodec A, Berkane N, Blandin V, Breittmayer JP, Ferrari E, Frelin C, Vigne P: Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism. Mol Pharmacol. 2000 Apr;57(4):797-804.@@Blandin V, Vigne P, Breittmayer JP, Frelin C: Allosteric inhibition of endothelin ETA receptors by 3, 5-dibromosalicylic acid. Mol Pharmacol. 2000 Dec;58(6):1461-9.@@Davenport AP, Hyndman KA, Dhaun N, Southan C, Kohan DE, Pollock JS, Pollock DM, Webb DJ, Maguire JJ: Endothelin. Pharmacol Rev. 2016 Apr;68(2):357-418. doi: 10.1124/pr.115.011833. |
Groups | Approved; Vet_approved |
Direct Classification | Acylsalicylic acids |
SMILES | CC(=O)OC1=CC=CC=C1C(O)=O |
Pathways | Acetylsalicylic Acid Action Pathway |
PharmGKB | PA448497 |
ChEMBL | CHEMBL25 |