Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10013568HBVENSG00000151617.17protein_codingEDNRANoNo1909P25101
TVIS20026127HPVENSG00000151617.17protein_codingEDNRANoNo1909P25101
TCGA Plot Options
Drug Information
GeneEDNRA
DrugBank IDDB00945
Drug NameAcetylsalicylic acid
Target IDBE0000521
UniProt IDP25101
Regulation Typeinhibitor
PubMed IDs10727528; 11093786; 26956245
CitationsTalbodec A, Berkane N, Blandin V, Breittmayer JP, Ferrari E, Frelin C, Vigne P: Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism. Mol Pharmacol. 2000 Apr;57(4):797-804.@@Blandin V, Vigne P, Breittmayer JP, Frelin C: Allosteric inhibition of endothelin ETA receptors by 3, 5-dibromosalicylic acid. Mol Pharmacol. 2000 Dec;58(6):1461-9.@@Davenport AP, Hyndman KA, Dhaun N, Southan C, Kohan DE, Pollock JS, Pollock DM, Webb DJ, Maguire JJ: Endothelin. Pharmacol Rev. 2016 Apr;68(2):357-418. doi: 10.1124/pr.115.011833.
GroupsApproved; Vet_approved
Direct ClassificationAcylsalicylic acids
SMILESCC(=O)OC1=CC=CC=C1C(O)=O
PathwaysAcetylsalicylic Acid Action Pathway
PharmGKBPA448497
ChEMBLCHEMBL25