| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013568 | HBV | ENSG00000151617.17 | protein_coding | EDNRA | No | No | 1909 | P25101 |
| TVIS20026127 | HPV | ENSG00000151617.17 | protein_coding | EDNRA | No | No | 1909 | P25101 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | EDNRA |
|---|---|
| DrugBank ID | DB04883 |
| Drug Name | Darusentan |
| Target ID | BE0000521 |
| UniProt ID | P25101 |
| Regulation Type | |
| PubMed IDs | 17890870; 17049116 |
| Citations | Orth SR, Schiele G, Banas B, Ritz E, Amann K: Effect of a selective endothelin receptor A blocker on cardiovascular remodeling in uninephrectomized spontaneously hypertensive rats of the stroke-prone strain. Kidney Blood Press Res. 2007;30(6):400-7. Epub 2007 Sep 20.@@Xia QG, Reinecke A, Dorenkamp M, Daemen MJ, Simon R, Unger T: Effects of endothelin ETA receptor blocker LU 135252 on cardiac remodeling and survival in a hypertensive rat model of chronic heart failure. Acta Pharmacol Sin. 2006 Nov;27(11):1417-22. |
| Groups | Investigational |
| Direct Classification | Diphenylmethanes |
| SMILES | COC1=CC(OC)=NC(O[C@H](C(O)=O)C(OC)(C2=CC=CC=C2)C2=CC=CC=C2)=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL23261 |
