| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017835 | HBV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS10049964 | HBV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS30004190 | HIV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS30079024 | HIV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS30075830 | HIV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS30082812 | HIV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS30020969 | HIV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS20007944 | HPV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS20063531 | HPV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
| TVIS20018278 | HPV | ENSG00000136928.7 | protein_coding | GABBR2 | No | No | 9568 | H9NIL8 O75899 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABBR2 |
|---|---|
| DrugBank ID | DB00363 |
| Drug Name | Clozapine |
| Target ID | BE0002340 |
| UniProt ID | O75899 |
| Regulation Type | positive modulator |
| PubMed IDs | 32203158 |
| Citations | Nair PC, McKinnon RA, Miners JO, Bastiampillai T: Binding of clozapine to the GABA(B) receptor: clinical and structural insights. Mol Psychiatry. 2020 Sep;25(9):1910-1919. doi: 10.1038/s41380-020-0709-5. Epub 2020 Mar 13. |
| Groups | Approved |
| Direct Classification | Dibenzodiazepines |
| SMILES | CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA449061 |
| ChEMBL | CHEMBL42 |
