| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015691 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS10026184 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30011403 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30004372 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30010128 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20032371 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20040966 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL2RA |
|---|---|
| DrugBank ID | DB00041 |
| Drug Name | Aldesleukin |
| Target ID | BE0000658 |
| UniProt ID | P01589 |
| Regulation Type | agonist |
| PubMed IDs | 17216565; 16767920; 17530023; 17584597; 16864089; 11752352; 10207608 |
| Citations | Waldmann TA: Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey. J Clin Immunol. 2007 Jan;27(1):1-18. Epub 2007 Jan 11.@@Recchia F, Cesta A, Rea S: Low dose interleukin-2 and 13-cis-retinoic acid as maintenance therapy in patients with solid tumors responsive to chemotherapy. J Exp Clin Cancer Res. 2003 Dec;22(4 Suppl):135-43.@@Waldmann TA: Daclizumab (anti-Tac, Zenapax) in the treatment of leukemia/lymphoma. Oncogene. 2007 May 28;26(25):3699-703.@@Vlad G, Ho EK, Vasilescu ER, Fan J, Liu Z, Cai JW, Jin Z, Burke E, Deng M, Cadeiras M, Cortesini R, Itescu S, Marboe C, Mancini D, Suciu-Foca N: Anti-CD25 treatment and FOXP3-positive regulatory T cells in heart transplantation. Transpl Immunol. 2007 Jul;18(1):13-21. Epub 2007 Apr 2.@@Liu BY, Zhu P, Luo HB, Fu N: [Screening of short peptides binding to cell surface interleukin-2 receptor alpha chain]. Nan Fang Yi Ke Da Xue Xue Bao. 2006 Jul;26(7):971-4.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Ouyang Y, Kaminski NE: Phospholipase A2 inhibitors p-bromophenacyl bromide and arachidonyl trifluoromethyl ketone suppressed interleukin-2 (IL-2) expression in murine primary splenocytes. Arch Toxicol. 1999 Feb;73(1):1-6. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA448081 |
| ChEMBL | CHEMBL1201438 |
