| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015691 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS10026184 | HBV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30011403 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30004372 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS30010128 | HIV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20032371 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
| TVIS20040966 | HPV | ENSG00000134460.19 | protein_coding | IL2RA | No | No | 3559 | P01589 Q5W005 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL2RA |
|---|---|
| DrugBank ID | DB00111 |
| Drug Name | Daclizumab |
| Target ID | BE0000658 |
| UniProt ID | P01589 |
| Regulation Type | antibody |
| PubMed IDs | 16304857; 10607689; 16908318; 8600944; 17564638; 19788505; 11752352 |
| Citations | Shamsi TS, Irfan M, Farzana T, Ansari SH, Ahmad G, Shakoor N, Baig MI: Allogeneic peripheral blood stem cell transplant (PBSCT) using anti-IL2 receptor antibody Daclizumab for the prevention of acute graft versus host disease in steroid refractory Diamond Blackfan anaemia: a case report. J Pak Med Assoc. 2005 Oct;55(10):454-5.@@Przepiorka D, Kernan NA, Ippoliti C, Papadopoulos EB, Giralt S, Khouri I, Lu JG, Gajewski J, Durett A, Cleary K, Champlin R, Andersson BS, Light S: Daclizumab, a humanized anti-interleukin-2 receptor alpha chain antibody, for treatment of acute graft-versus-host disease. Blood. 2000 Jan 1;95(1):83-9.@@Garcia CD, Bittencourt VB, Tumelero A, Antonello JS, Malheiros D, Garcia VD: Plasmapheresis for recurrent posttransplant focal segmental glomerulosclerosis. Transplant Proc. 2006 Jul-Aug;38(6):1904-5.@@Krouwels FH, van der Heijden JF, Lutter R, van Neerven RJ, Jansen HM, Out TA: Glucocorticosteroids affect functions of airway- and blood-derived human T-cell clones, favoring the Th1 profile through two mechanisms. Am J Respir Cell Mol Biol. 1996 Apr;14(4):388-97.@@Patlolla V, Zhong X, Reed GW, Mandelbrot DA: Efficacy of anti-IL-2 receptor antibodies compared to no induction and to antilymphocyte antibodies in renal transplantation. Am J Transplant. 2007 Jul;7(7):1832-42.@@Monti P, Brigatti C, Heninger AK, Scirpoli M, Bonifacio E: Disengaging the IL-2 receptor with daclizumab enhances IL-7-mediated proliferation of CD4(+) and CD8(+) T cells. Am J Transplant. 2009 Dec;9(12):2727-35. doi: 10.1111/j.1600-6143.2009.02825.x. Epub 2009 Sep 25.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Investigational; Withdrawn |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164764446 |
| ChEMBL | CHEMBL1201605 |
