| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015984 | HBV | ENSG00000178035.13 | protein_coding | IMPDH2 | No | No | 3615 | P12268 |
| TVIS10029281 | HBV | ENSG00000178035.13 | protein_coding | IMPDH2 | No | No | 3615 | P12268 |
| TVIS10047149 | HBV | ENSG00000178035.13 | protein_coding | IMPDH2 | No | No | 3615 | P12268 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IMPDH2 |
|---|---|
| DrugBank ID | DB00688 |
| Drug Name | Mycophenolate mofetil |
| Target ID | BE0000722 |
| UniProt ID | P12268 |
| Regulation Type | inhibitor |
| PubMed IDs | 15621150; 17463174; 15803924 |
| Citations | Vannozzi F, Filipponi F, Di Paolo A, Danesi R, Urbani L, Bocci G, Catalano G, De Simone P, Mosca F, Del Tacca M: An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients. Transplant Proc. 2004 Nov;36(9):2787-90.@@Bremer S, Rootwelt H, Bergan S: Real-time PCR determination of IMPDH1 and IMPDH2 expression in blood cells. Clin Chem. 2007 Jun;53(6):1023-9. Epub 2007 Apr 26.@@Allison AC: Mechanisms of action of mycophenolate mofetil. Lupus. 2005;14 Suppl 1:s2-8. |
| Groups | Approved; Investigational |
| Direct Classification | Phthalides |
| SMILES | COC1=C(CC=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C |
| Pathways | Mycophenolic Acid Metabolism Pathway |
| PharmGKB | PA450566 |
| ChEMBL | CHEMBL1456 |
