| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30000919 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30003372 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30008116 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30001152 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30003373 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30008117 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30083303 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30055141 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30055142 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS30055143 | HIV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAPK1 |
|---|---|
| DrugBank ID | DB01169 |
| Drug Name | Arsenic trioxide |
| Target ID | BE0000923 |
| UniProt ID | P28482 |
| Regulation Type | inducer |
| PubMed IDs | 12426127; 12529330 |
| Citations | Dong Z: The molecular mechanisms of arsenic-induced cell transformation and apoptosis. Environ Health Perspect. 2002 Oct;110 Suppl 5:757-9.@@He Z, Ma WY, Liu G, Zhang Y, Bode AM, Dong Z: Arsenite-induced phosphorylation of histone H3 at serine 10 is mediated by Akt1, extracellular signal-regulated kinase 2, and p90 ribosomal S6 kinase 2 but not mitogen- and stress-activated protein kinase 1. J Biol Chem. 2003 Mar 21;278(12):10588-93. Epub 2003 Jan 14. |
| Groups | Approved; Investigational |
| Direct Classification | Metalloid oxides |
| SMILES | O=[As]O[As]=O |
| Pathways | |
| PharmGKB | PA448486 |
| ChEMBL | CHEMBL1200978 |
