| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30007269 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS30000178 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS30017582 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS20020716 | HPV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS20020717 | HPV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE6G |
|---|---|
| DrugBank ID | DB00820 |
| Drug Name | Tadalafil |
| Target ID | BE0003556 |
| UniProt ID | P18545 |
| Regulation Type | inhibitor |
| PubMed IDs | 29667180 |
| Citations | Andersson KE: PDE5 inhibitors - pharmacology and clinical applications 20 years after sildenafil discovery. Br J Pharmacol. 2018 Jul;175(13):2554-2565. doi: 10.1111/bph.14205. Epub 2018 Apr 25. |
| Groups | Approved; Investigational |
| Direct Classification | Beta carbolines |
| SMILES | [H][C@]12CC3=C(NC4=CC=CC=C34)[C@H](N1C(=O)CN(C)C2=O)C1=CC2=C(OCO2)C=C1 |
| Pathways | |
| PharmGKB | PA10333 |
| ChEMBL | CHEMBL779 |
