| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30007269 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS30000178 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS30017582 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS20020716 | HPV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS20020717 | HPV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE6G |
|---|---|
| DrugBank ID | DB00862 |
| Drug Name | Vardenafil |
| Target ID | BE0003556 |
| UniProt ID | P18545 |
| Regulation Type | inhibitor |
| PubMed IDs | 18779324 |
| Citations | Zhang XJ, Cahill KB, Elfenbein A, Arshavsky VY, Cote RH: Direct allosteric regulation between the GAF domain and catalytic domain of photoreceptor phosphodiesterase PDE6. J Biol Chem. 2008 Oct 31;283(44):29699-705. doi: 10.1074/jbc.M803948200. Epub 2008 Sep 8. |
| Groups | Approved |
| Direct Classification | Benzenesulfonamides |
| SMILES | CCCC1=NC(C)=C2N1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(CC)CC1 |
| Pathways | |
| PharmGKB | PA10229 |
| ChEMBL | CHEMBL1520 |
