| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44045368 | HTLV-1 | ENSG00000112033.14 | protein_coding | PPARD | No | No | 5467 | Q03181 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PPARD |
|---|---|
| DrugBank ID | DB00159 |
| Drug Name | Icosapent |
| Target ID | BE0001007 |
| UniProt ID | Q03181 |
| Regulation Type | agonist |
| PubMed IDs | 11552681; 10198642; 17632107; 9610365; 16507691 |
| Citations | Iwata Y, Miyamoto S, Takamura M, Yanagisawa H, Kasuya A: Interaction between peroxisome proliferator-activated receptor gamma and its agonists: docking study of oximes having 5-benzyl-2,4-thiazolidinedione. J Mol Graph Model. 2001;19(6):536-42, 598-600.@@Xu HE, Lambert MH, Montana VG, Parks DJ, Blanchard SG, Brown PJ, Sternbach DD, Lehmann JM, Wisely GB, Willson TM, Kliewer SA, Milburn MV: Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell. 1999 Mar;3(3):397-403.@@Kondo H, Misaki R, Gelman L, Watabe S: Ligand-dependent transcriptional activities of four torafugu pufferfish Takifugu rubripes peroxisome proliferator-activated receptors. Gen Comp Endocrinol. 2007 Oct-Dec;154(1-3):120-7. Epub 2007 Jun 12.@@Inoue I, Shino K, Noji S, Awata T, Katayama S: Expression of peroxisome proliferator-activated receptor alpha (PPAR alpha) in primary cultures of human vascular endothelial cells. Biochem Biophys Res Commun. 1998 May 19;246(2):370-4.@@Caldari-Torres C, Rodriguez-Sallaberry C, Greene ES, Badinga L: Differential effects of n-3 and n-6 fatty acids on prostaglandin F2alpha production by bovine endometrial cells. J Dairy Sci. 2006 Mar;89(3):971-7. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Long-chain fatty acids |
| SMILES | CCC=C/CC=C/CC=C/CC=C/CC=C/CCCC(O)=O |
| Pathways | Alpha Linolenic Acid and Linoleic Acid Metabolism |
| PharmGKB | PA164746077 |
| ChEMBL | CHEMBL460026 |
