| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30079525 | HIV | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
| TVIS30027580 | HIV | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
| TVIS20046217 | HPV | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
| TVIS44026438 | HTLV-1 | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | RET |
|---|---|
| DrugBank ID | DB00619 |
| Drug Name | Imatinib |
| Target ID | BE0002411 |
| UniProt ID | P07949 |
| Regulation Type | inhibitor |
| PubMed IDs | 16782438 |
| Citations | de Groot JW, Plaza Menacho I, Schepers H, Drenth-Diephuis LJ, Osinga J, Plukker JT, Links TP, Eggen BJ, Hofstra RM: Cellular effects of imatinib on medullary thyroid cancer cells harboring multiple endocrine neoplasia Type 2A and 2B associated RET mutations. Surgery. 2006 Jun;139(6):806-14. |
| Groups | Approved |
| Direct Classification | Benzanilides |
| SMILES | CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1 |
| Pathways | Imatinib Inhibition of BCR-ABL |
| PharmGKB | PA10804 |
| ChEMBL | CHEMBL941 |
