| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30079525 | HIV | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
| TVIS30027580 | HIV | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
| TVIS20046217 | HPV | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
| TVIS44026438 | HTLV-1 | ENSG00000165731.22 | protein_coding | RET | Yes | No | 5979 | P07949 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | RET |
|---|---|
| DrugBank ID | DB08875 |
| Drug Name | Cabozantinib |
| Target ID | BE0002411 |
| UniProt ID | P07949 |
| Regulation Type | antagonist |
| PubMed IDs | 21606412 |
| Citations | Kurzrock R, Sherman SI, Ball DW, Forastiere AA, Cohen RB, Mehra R, Pfister DG, Cohen EE, Janisch L, Nauling F, Hong DS, Ng CS, Ye L, Gagel RF, Frye J, Muller T, Ratain MJ, Salgia R: Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer. J Clin Oncol. 2011 Jul 1;29(19):2660-6. doi: 10.1200/JCO.2010.32.4145. Epub 2011 May 23. |
| Groups | Approved; Investigational |
| Direct Classification | Diarylethers |
| SMILES | COC1=CC2=C(C=C1OC)C(OC1=CC=C(NC(=O)C3(CC3)C(=O)NC3=CC=C(F)C=C3)C=C1)=CC=N2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2105717 |
