| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20020555 | HPV | ENSG00000180616.9 | protein_coding | SSTR2 | No | No | 6752 | P30874 |
| TVIS20020556 | HPV | ENSG00000180616.9 | protein_coding | SSTR2 | No | No | 6752 | P30874 |
| TVIS44018052 | HTLV-1 | ENSG00000180616.9 | protein_coding | SSTR2 | No | No | 6752 | P30874 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SSTR2 |
|---|---|
| DrugBank ID | DB06663 |
| Drug Name | Pasireotide |
| Target ID | BE0003528 |
| UniProt ID | P30874 |
| Regulation Type | |
| PubMed IDs | 17395978; 11980628 |
| Citations | Zatelli MC, Piccin D, Vignali C, Tagliati F, Ambrosio MR, Bondanelli M, Cimino V, Bianchi A, Schmid HA, Scanarini M, Pontecorvi A, De Marinis L, Maira G, degli Uberti EC: Pasireotide, a multiple somatostatin receptor subtypes ligand, reduces cell viability in non-functioning pituitary adenomas by inhibiting vascular endothelial growth factor secretion. Endocr Relat Cancer. 2007 Mar;14(1):91-102.@@Bruns C, Lewis I, Briner U, Meno-Tetang G, Weckbecker G: SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur J Endocrinol. 2002 May;146(5):707-16. |
| Groups | Approved |
| Direct Classification | Oligopeptides |
| SMILES | NCCCC[C@@H]1NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@@H](NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(OCC3=CC=CC=C3)C=C2)NC1=O)OC(=O)NCCN)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3349607 |
