Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20020555HPVENSG00000180616.9protein_codingSSTR2NoNo6752P30874
TVIS20020556HPVENSG00000180616.9protein_codingSSTR2NoNo6752P30874
TVIS44018052HTLV-1ENSG00000180616.9protein_codingSSTR2NoNo6752P30874
TCGA Plot Options
Drug Information
GeneSSTR2
DrugBank IDDB13985
Drug NameLutetium Lu 177 dotatate
Target IDBE0003528
UniProt IDP30874
Regulation Typeagonist
PubMed IDs22388631
CitationsKam BL, Teunissen JJ, Krenning EP, de Herder WW, Khan S, van Vliet EI, Kwekkeboom DJ: Lutetium-labelled peptides for therapy of neuroendocrine tumours. Eur J Nucl Med Mol Imaging. 2012 Feb;39 Suppl 1:S103-12. doi: 10.1007/s00259-011-2039-y.
GroupsApproved; Investigational
Direct Classification
SMILES[177Lu+3].C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)CN2CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CC2=CNC3=C2C=CC=C3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(O)=O
Pathways
PharmGKB
ChEMBL