| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10031922 | HBV | ENSG00000196664.5 | protein_coding | TLR7 | No | No | 51284 | B2R9N9 Q9NYK1 |
| TVIS20038474 | HPV | ENSG00000196664.5 | protein_coding | TLR7 | No | No | 51284 | B2R9N9 Q9NYK1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TLR7 |
|---|---|
| DrugBank ID | DB01611 |
| Drug Name | Hydroxychloroquine |
| Target ID | BE0000155 |
| UniProt ID | Q9NYK1 |
| Regulation Type | antagonist |
| PubMed IDs | 18220957; 14579285 |
| Citations | Sun S, Rao NL, Venable J, Thurmond R, Karlsson L: TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders. Inflamm Allergy Drug Targets. 2007 Dec;6(4):223-35.@@Trevani AS, Chorny A, Salamone G, Vermeulen M, Gamberale R, Schettini J, Raiden S, Geffner J: Bacterial DNA activates human neutrophils by a CpG-independent pathway. Eur J Immunol. 2003 Nov;33(11):3164-74. |
| Groups | Approved |
| Direct Classification | 4-aminoquinolines |
| SMILES | CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1 |
| Pathways | |
| PharmGKB | PA164777036 |
| ChEMBL | CHEMBL1535 |
