| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10031922 | HBV | ENSG00000196664.5 | protein_coding | TLR7 | No | No | 51284 | B2R9N9 Q9NYK1 |
| TVIS20038474 | HPV | ENSG00000196664.5 | protein_coding | TLR7 | No | No | 51284 | B2R9N9 Q9NYK1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TLR7 |
|---|---|
| DrugBank ID | DB04860 |
| Drug Name | Isatoribine |
| Target ID | BE0000155 |
| UniProt ID | Q9NYK1 |
| Regulation Type | |
| PubMed IDs | 16116638 |
| Citations | Horsmans Y, Berg T, Desager JP, Mueller T, Schott E, Fletcher SP, Steffy KR, Bauman LA, Kerr BM, Averett DR: Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection. Hepatology. 2005 Sep;42(3):724-31. |
| Groups | Investigational |
| Direct Classification | Glycosylamines |
| SMILES | NC1=NC(=O)C2=C(N1)N([C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)S2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2105116 |
