| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009597 | HBV | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
| TVIS10011300 | HBV | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
| TVIS10041989 | HBV | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
| TVIS30051950 | HIV | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
| TVIS20000113 | HPV | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
| TVIS20001686 | HPV | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
| TVIS44048722 | HTLV-1 | ENSG00000064989.13 | protein_coding | CALCRL | No | No | 10203 | Q16602 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CALCRL |
|---|---|
| DrugBank ID | DB12457 |
| Drug Name | Rimegepant |
| Target ID | BE0009009 |
| UniProt ID | Q16602 |
| Regulation Type | antagonist |
| PubMed IDs | 31291516; 31081399 |
| Citations | Lipton RB, Croop R, Stock EG, Stock DA, Morris BA, Frost M, Dubowchik GM, Conway CM, Coric V, Goadsby PJ: Rimegepant, an Oral Calcitonin Gene-Related Peptide Receptor Antagonist, for Migraine. N Engl J Med. 2019 Jul 11;381(2):142-149. doi: 10.1056/NEJMoa1811090.@@Negro A, Martelletti P: Gepants for the treatment of migraine. Expert Opin Investig Drugs. 2019 Jun;28(6):555-567. doi: 10.1080/13543784.2019.1618830. Epub 2019 May 17. |
| Groups | Approved; Investigational |
| Direct Classification | Imidazopyridines |
| SMILES | N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)N2C(=O)NC3=NC=CC=C23)C2=C1C=CC=N2)C1=C(F)C(F)=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2178422 |
