Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10009597HBVENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TVIS10011300HBVENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TVIS10041989HBVENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TVIS30051950HIVENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TVIS20000113HPVENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TVIS20001686HPVENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TVIS44048722HTLV-1ENSG00000064989.13protein_codingCALCRLNoNo10203Q16602
TCGA Plot Options
Drug Information
GeneCALCRL
DrugBank IDDB15688
Drug NameZavegepant
Target IDBE0009009
UniProt IDQ16602
Regulation Typeantagonist
PubMed IDs33096162; 35774914
CitationsMercer SE, Chaturvedula PV, Conway CM, Cook DA, Davis CD, Pin SS, Macci R, Schartman R, Signor LJ, Widmann KA, Whiterock VJ, Chen P, Xu C, Herbst JJ, Kostich WA, Thalody G, Macor JE, Dubowchik GM: Azepino-indazoles as calcitonin gene-related peptide (CGRP) receptor antagonists. Bioorg Med Chem Lett. 2021 Jan 1;31:127624. doi: 10.1016/j.bmcl.2020.127624. Epub 2020 Oct 21.@@Noor N, Angelette A, Lawson A, Patel A, Urits I, Viswanath O, Yazdi C, Kaye AD: A Comprehensive Review of Zavegepant as Abortive Treatment for Migraine. Health Psychol Res. 2022 Jun 28;10(3):35506. doi: 10.52965/001c.35506. eCollection 2022.
GroupsApproved; Investigational
Direct Classification
SMILESCN1CCC(CC1)N1CCN(CC1)C(=O)[C@@H](CC1=CC2=C(NN=C2)C(C)=C1)NC(=O)N1CCC(CC1)C1=CC2=C(NC1=O)C=CC=C2
Pathways
PharmGKB
ChEMBLCHEMBL2397415