| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30068863 | HIV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS30068864 | HIV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS30068865 | HIV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20000889 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20024504 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20066292 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20020491 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS44022865 | HTLV-1 | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | IKBKB |
|---|---|
| DrugBank ID | DB00945 |
| Drug Name | Acetylsalicylic acid |
| Target ID | BE0001154 |
| UniProt ID | O14920 |
| Regulation Type | |
| PubMed IDs | 24874482; 10779355; 29079505; 21797846; 11160126; 14755344 |
| Citations | Alfonso L, Ai G, Spitale RC, Bhat GJ: Molecular targets of aspirin and cancer prevention. Br J Cancer. 2014 Jul 8;111(1):61-7. doi: 10.1038/bjc.2014.271. Epub 2014 May 29.@@Yamamoto Y, Yin MJ, Gaynor RB: IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity. Mol Cell Biol. 2000 May;20(10):3655-66.@@Konig HG, Watters O, Kinsella S, Ameen M, Fenner BJ, Prehn JHM: A constitutively-active IKK-complex at the axon initial segment. Brain Res. 2018 Jan 1;1678:356-366. doi: 10.1016/j.brainres.2017.10.020. Epub 2017 Oct 24.@@Gamble C, McIntosh K, Scott R, Ho KH, Plevin R, Paul A: Inhibitory kappa B Kinases as targets for pharmacological regulation. Br J Pharmacol. 2012 Feb;165(4):802-19. doi: 10.1111/j.1476-5381.2011.01608.x.@@Yamamoto Y, Gaynor RB: Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest. 2001 Jan;107(2):135-42. doi: 10.1172/JCI11914.@@Rohl M, Pasparakis M, Baudler S, Baumgartl J, Gautam D, Huth M, De Lorenzi R, Krone W, Rajewsky K, Bruning JC: Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance. J Clin Invest. 2004 Feb;113(3):474-81. doi: 10.1172/JCI18712. |
| Groups | Approved; Vet_approved |
| Direct Classification | Acylsalicylic acids |
| SMILES | CC(=O)OC1=CC=CC=C1C(O)=O |
| Pathways | Acetylsalicylic Acid Action Pathway |
| PharmGKB | PA448497 |
| ChEMBL | CHEMBL25 |
