| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30068863 | HIV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS30068864 | HIV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS30068865 | HIV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20000889 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20024504 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20066292 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS20020491 | HPV | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
| TVIS44022865 | HTLV-1 | ENSG00000104365.16 | protein_coding | IKBKB | No | No | 3551 | O14920 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IKBKB |
|---|---|
| DrugBank ID | DB00995 |
| Drug Name | Auranofin |
| Target ID | BE0001154 |
| UniProt ID | O14920 |
| Regulation Type | inhibitor |
| PubMed IDs | 12754408; 17034761 |
| Citations | Jeon KI, Byun MS, Jue DM: Gold compound auranofin inhibits IkappaB kinase (IKK) by modifying Cys-179 of IKKbeta subunit. Exp Mol Med. 2003 Apr 30;35(2):61-6.@@Youn HS, Lee JY, Saitoh SI, Miyake K, Hwang DH: Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4. Biochem Biophys Res Commun. 2006 Dec 1;350(4):866-71. Epub 2006 Sep 28. |
| Groups | Approved; Investigational |
| Direct Classification | Tetracarboxylic acids and derivatives |
| SMILES | CCP(CC)(CC)=[Au]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O |
| Pathways | |
| PharmGKB | PA448510 |
| ChEMBL | CHEMBL1366 |
