| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009167 | HBV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS20012030 | HPV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS20036049 | HPV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS20056806 | HPV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS44025067 | HTLV-1 | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN5A |
|---|---|
| DrugBank ID | DB00280 |
| Drug Name | Disopyramide |
| Target ID | BE0000197 |
| UniProt ID | Q14524 |
| Regulation Type | inhibitor |
| PubMed IDs | 15897781; 15028073; 11196553; 11752352 |
| Citations | Sugao M, Fujiki A, Nishida K, Sakabe M, Tsuneda T, Iwamoto J, Mizumaki K, Inoue H: Repolarization dynamics in patients with idiopathic ventricular fibrillation: pharmacological therapy with bepridil and disopyramide. J Cardiovasc Pharmacol. 2005 Jun;45(6):545-9.@@Fujiki A, Sugao M, Nishida K, Sakabe M, Tsuneda T, Mizumaki K, Inoue H: Repolarization abnormality in idiopathic ventricular fibrillation: assessment using 24-hour QT-RR and QaT-RR relationships. J Cardiovasc Electrophysiol. 2004 Jan;15(1):59-63.@@Shimizu W, Antzelevitch C, Suyama K, Kurita T, Taguchi A, Aihara N, Takaki H, Sunagawa K, Kamakura S: Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. J Cardiovasc Electrophysiol. 2000 Dec;11(12):1320-9.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Pheniramines |
| SMILES | CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C1=NC=CC=C1)C(C)C |
| Pathways | Disopyramide Action Pathway |
| PharmGKB | PA449373 |
| ChEMBL | CHEMBL517 |
