| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30016613 | HIV | ENSG00000104549.12 | protein_coding | SQLE | No | No | 6713 | Q14534 Q9UNR6 |
| TVIS30016614 | HIV | ENSG00000104549.12 | protein_coding | SQLE | No | No | 6713 | Q14534 Q9UNR6 |
| TVIS30021692 | HIV | ENSG00000104549.12 | protein_coding | SQLE | No | No | 6713 | Q14534 Q9UNR6 |
| TVIS30069809 | HIV | ENSG00000104549.12 | protein_coding | SQLE | No | No | 6713 | Q14534 Q9UNR6 |
| TVIS30069810 | HIV | ENSG00000104549.12 | protein_coding | SQLE | No | No | 6713 | Q14534 Q9UNR6 |
| TVIS30069811 | HIV | ENSG00000104549.12 | protein_coding | SQLE | No | No | 6713 | Q14534 Q9UNR6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SQLE |
|---|---|
| DrugBank ID | DB01091 |
| Drug Name | Butenafine |
| Target ID | BE0000577 |
| UniProt ID | Q14534 |
| Regulation Type | inhibitor |
| PubMed IDs | 12499173; 16079485; 18624686; 17642865; 8494375; 11752352 |
| Citations | Mukherjee PK, Leidich SD, Isham N, Leitner I, Ryder NS, Ghannoum MA: Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine. Antimicrob Agents Chemother. 2003 Jan;47(1):82-6.@@Gao PH, Cao YB, Xu Z, Zhang JD, Zhang WN, Wang Y, Gu J, Cao YY, Li RY, Jia XM, Jiang YY: In vitro antifungal activity of ZJ-522, a new triazole restructured from fluconazole and butenafine, against clinically important fungi in comparison with fluconazole and butenafine. Biol Pharm Bull. 2005 Aug;28(8):1414-7.@@Singal A: Butenafine and superficial mycoses: current status. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005. doi: 10.1517/17425255.4.7.999 .@@Ramam M, Prasad HR, Manchanda Y, Khaitan BK, Banerjee U, Mukhopadhyaya A, Shetty R, Gogtay JA: Randomised controlled trial of topical butenafine in tinea cruris and tinea corporis. Indian J Dermatol Venereol Leprol. 2003 Mar-Apr;69(2):154-8.@@Iwatani W, Arika T, Yamaguchi H: Two mechanisms of butenafine action in Candida albicans. Antimicrob Agents Chemother. 1993 Apr;37(4):785-8.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Naphthalenes |
| SMILES | CN(CC1=CC=C(C=C1)C(C)(C)C)CC1=CC=CC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA164745478 |
| ChEMBL | CHEMBL990 |
