| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44050523 | HTLV-1 | ENSG00000232810.5 | protein_coding | TNF | No | No | 7124 | P01375 Q5STB3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TNF |
|---|---|
| DrugBank ID | DB11752 |
| Drug Name | Bryostatin 1 |
| Target ID | BE0000704 |
| UniProt ID | P01375 |
| Regulation Type | inducer |
| PubMed IDs | 25808573 |
| Citations | Kedei N, Kraft MB, Keck GE, Herald CL, Melody N, Pettit GR, Blumberg PM: Neristatin 1 provides critical insight into bryostatin 1 structure-function relationships. J Nat Prod. 2015 Apr 24;78(4):896-900. doi: 10.1021/acs.jnatprod.5b00094. Epub 2015 Mar 26. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | [H][C@]12C[C@H](OC(C)=O)C(C)(C)[C@](O)(C[C@]3([H])CC(C[C@@]([H])(O3)C=CC(C)(C)[C@]3(O)O[C@@]([H])(CC(=C/C(=O)OC)[C@@H]3OC(=O)C=CC=CCCC)C[C@@]([H])(OC(=O)C[C@H](O)C1)[C@@H](C)O)=CC(=O)OC)O2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL449158 |
