| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44050523 | HTLV-1 | ENSG00000232810.5 | protein_coding | TNF | No | No | 7124 | P01375 Q5STB3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TNF |
|---|---|
| DrugBank ID | DB01407 |
| Drug Name | Clenbuterol |
| Target ID | BE0000704 |
| UniProt ID | P01375 |
| Regulation Type | other/unknown |
| PubMed IDs | 10071758; 11193379; 15021963; 16261833; 17139543 |
| Citations | Izeboud CA, Mocking JA, Monshouwer M, van Miert AS, Witkamp RF: Participation of beta-adrenergic receptors on macrophages in modulation of LPS-induced cytokine release. J Recept Signal Transduct Res. 1999 Jan-Jul;19(1-4):191-202.@@Yoshimura T: [Modulation of cytokine production from human mononuclear cells by several agents]. Yakugaku Zasshi. 2000 Dec;120(12):1277-90.@@Izeboud CA, Hoebe KH, Grootendorst AF, Nijmeijer SM, van Miert AS, Witkamp RR, Rodenburg RJ: Endotoxin-induced liver damage in rats is minimized by beta 2-adrenoceptor stimulation. Inflamm Res. 2004 Mar;53(3):93-9. Epub 2004 Feb 16.@@Laan TT, Bull S, Pirie RS, Fink-Gremmels J: Evaluation of cytokine production by equine alveolar macrophages exposed to lipopolysaccharide, Aspergillus fumigatus, and a suspension of hay dust. Am J Vet Res. 2005 Sep;66(9):1584-9.@@van den Hoven R, Duvigneau JC, Hartl RT, Gemeiner M: Clenbuterol affects the expression of messenger RNA for interleukin 10 in peripheral leukocytes from horses challenged intrabronchially with lipopolysaccharides. Vet Res Commun. 2006 Nov;30(8):921-8. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Dichlorobenzenes |
| SMILES | CC(C)(C)NCC(O)C1=CC(Cl)=C(N)C(Cl)=C1 |
| Pathways | |
| PharmGKB | PA164745640 |
| ChEMBL | CHEMBL49080 |
