| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44050523 | HTLV-1 | ENSG00000232810.5 | protein_coding | TNF | No | No | 7124 | P01375 Q5STB3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TNF |
|---|---|
| DrugBank ID | DB00668 |
| Drug Name | Epinephrine |
| Target ID | BE0000704 |
| UniProt ID | P01375 |
| Regulation Type | antagonist |
| PubMed IDs | 8609227; 7733399 |
| Citations | van der Poll T, Coyle SM, Barbosa K, Braxton CC, Lowry SF: Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. J Clin Invest. 1996 Feb 1;97(3):713-9.@@Liao J, Keiser JA, Scales WE, Kunkel SL, Kluger MJ: Role of epinephrine in TNF and IL-6 production from isolated perfused rat liver. Am J Physiol. 1995 Apr;268(4 Pt 2):R896-901. doi: 10.1152/ajpregu.1995.268.4.R896. |
| Groups | Approved; Vet_approved |
| Direct Classification | Catechols |
| SMILES | CNC[C@H](O)C1=CC(O)=C(O)C=C1 |
| Pathways | Tyrosine Metabolism; Disulfiram Action Pathway; Aromatic L-Aminoacid Decarboxylase Deficiency; Monoamine Oxidase-A Deficiency (MAO-A); Catecholamine Biosynthesis; Tyrosinemia, Transient, of the Newborn; Hawkinsinuria; Dopamine beta-Hydroxylase Deficiency; Tyrosinemia Type I; Epinephrine Action Pathway; Alkaptonuria; Tyrosine Hydroxylase Deficiency |
| PharmGKB | PA449470 |
| ChEMBL | CHEMBL679 |
