| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30043802 | HIV | ENSG00000131747.15 | protein_coding | TOP2A | Yes | No | 7153 | P11388 |
| TVIS44051346 | HTLV-1 | ENSG00000131747.15 | protein_coding | TOP2A | Yes | No | 7153 | P11388 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TOP2A |
|---|---|
| DrugBank ID | DB09047 |
| Drug Name | Finafloxacin |
| Target ID | BE0000742 |
| UniProt ID | P11388 |
| Regulation Type | inhibitor |
| PubMed IDs | 25808831 |
| Citations | McKeage K: Finafloxacin: first global approval. Drugs. 2015 Apr;75(6):687-93. doi: 10.1007/s40265-015-0384-z. |
| Groups | Approved; Investigational |
| Direct Classification | Quinoline carboxylic acids |
| SMILES | [H][C@]12CN(C[C@]1([H])OCCN2)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1C#N)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1908370 |
