| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30043802 | HIV | ENSG00000131747.15 | protein_coding | TOP2A | Yes | No | 7153 | P11388 |
| TVIS44051346 | HTLV-1 | ENSG00000131747.15 | protein_coding | TOP2A | Yes | No | 7153 | P11388 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | TOP2A |
|---|---|
| DrugBank ID | DB00467 |
| Drug Name | Enoxacin |
| Target ID | BE0000742 |
| UniProt ID | P11388 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 18471102; 10089819 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Maki T, Hirono I, Kondo H, Aoki T: Drug resistance mechanism of the fish-pathogenic bacterium Lactococcus garvieae. J Fish Dis. 2008 Jun;31(6):461-8. doi: 10.1111/j.1365-2761.2008.00927.x.@@Snyder RD, Cooper CS: Photogenotoxicity of fluoroquinolones in Chinese hamster V79 cells: dependency on active topoisomerase II. Photochem Photobiol. 1999 Mar;69(3):288-93. |
| Groups | Approved; Investigational |
| Direct Classification | Naphthyridine carboxylic acids and derivatives |
| SMILES | CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N=C12)N1CCNCC1 |
| Pathways | |
| PharmGKB | PA449462 |
| ChEMBL | CHEMBL826 |
