| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10036751 | HBV | ENSG00000136160.17 | protein_coding | EDNRB | No | No | 1910 | P24530 |
| TVIS10050050 | HBV | ENSG00000136160.17 | protein_coding | EDNRB | No | No | 1910 | P24530 |
| TVIS30035474 | HIV | ENSG00000136160.17 | protein_coding | EDNRB | No | No | 1910 | P24530 |
| TVIS20046672 | HPV | ENSG00000136160.17 | protein_coding | EDNRB | No | No | 1910 | P24530 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | EDNRB |
|---|---|
| DrugBank ID | DB06403 |
| Drug Name | Ambrisentan |
| Target ID | BE0000043 |
| UniProt ID | P24530 |
| Regulation Type | antagonist |
| PubMed IDs | 19920913; 19601701 |
| Citations | Casserly B, Klinger JR: Ambrisentan for the treatment of pulmonary arterial hypertension. Drug Des Devel Ther. 2009 Feb 6;2:265-80.@@Kingman M, Ruggiero R, Torres F: Ambrisentan, an endothelin receptor type A-selective endothelin receptor antagonist, for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother. 2009 Aug;10(11):1847-58. doi: 10.1517/14656560903061275. |
| Groups | Approved; Investigational |
| Direct Classification | Diphenylmethanes |
| SMILES | COC([C@H](OC1=NC(C)=CC(C)=N1)C(O)=O)(C1=CC=CC=C1)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA165860521 |
| ChEMBL | CHEMBL1111 |
