| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30013942 | HIV | ENSG00000105639.21 | protein_coding | JAK3 | Yes | No | 3718 | P52333 |
| TVIS30074295 | HIV | ENSG00000105639.21 | protein_coding | JAK3 | Yes | No | 3718 | P52333 |
| TVIS30048296 | HIV | ENSG00000105639.21 | protein_coding | JAK3 | Yes | No | 3718 | P52333 |
| TVIS30048297 | HIV | ENSG00000105639.21 | protein_coding | JAK3 | Yes | No | 3718 | P52333 |
| TVIS20007387 | HPV | ENSG00000105639.21 | protein_coding | JAK3 | Yes | No | 3718 | P52333 |
| TVIS20007388 | HPV | ENSG00000105639.21 | protein_coding | JAK3 | Yes | No | 3718 | P52333 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | JAK3 |
|---|---|
| DrugBank ID | DB08895 |
| Drug Name | Tofacitinib |
| Target ID | BE0003493 |
| UniProt ID | P52333 |
| Regulation Type | inhibitor |
| PubMed IDs | 10592235 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Investigational |
| Direct Classification | N-acylpiperidines |
| SMILES | C[C@@H]1CCN(C[C@@H]1N(C)C1=NC=NC2=C1C=CN2)C(=O)CC#N |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL221959 |
