| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30058638 | HIV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS30020716 | HIV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS30058639 | HIV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS20036587 | HPV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS20023553 | HPV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | P2RY12 |
|---|---|
| DrugBank ID | DB01240 |
| Drug Name | Epoprostenol |
| Target ID | BE0000110 |
| UniProt ID | Q9H244 |
| Regulation Type | agonist |
| PubMed IDs | 17155953; 12297509; 20085435 |
| Citations | Cattaneo M, Lecchi A: Inhibition of the platelet P2Y12 receptor for adenosine diphosphate potentiates the antiplatelet effect of prostacyclin. J Thromb Haemost. 2007 Mar;5(3):577-82. Epub 2006 Dec 7.@@Yang J, Wu J, Jiang H, Mortensen R, Austin S, Manning DR, Woulfe D, Brass LF: Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors. J Biol Chem. 2002 Nov 29;277(48):46035-42. Epub 2002 Sep 23.@@Kobsar AL, Koessler J, Rajkovic MS, Brunner KP, Steigerwald U, Walter U: Prostacyclin receptor stimulation facilitates detection of human platelet P2Y(12) receptor inhibition by the PFA-100 system. Platelets. 2010;21(2):112-6. doi: 10.3109/09537100903440937. |
| Groups | Approved |
| Direct Classification | |
| SMILES | [H][C@]12C[C@@H](O)[C@H](C=C[C@@H](O)CCCCC)[C@@]1([H])CC(O2)=CCCCC(O)=O |
| Pathways | |
| PharmGKB | PA449479 |
| ChEMBL | CHEMBL1139 |
