| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30058638 | HIV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS30020716 | HIV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS30058639 | HIV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS20036587 | HPV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
| TVIS20023553 | HPV | ENSG00000169313.10 | protein_coding | P2RY12 | No | No | 64805 | Q9H244 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | P2RY12 |
|---|---|
| DrugBank ID | DB08816 |
| Drug Name | Ticagrelor |
| Target ID | BE0000110 |
| UniProt ID | Q9H244 |
| Regulation Type | inhibitor |
| PubMed IDs | 26063049; 30883047 |
| Citations | Teng R: Ticagrelor: Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Profile: An Update. Clin Pharmacokinet. 2015 Nov;54(11):1125-38. doi: 10.1007/s40262-015-0290-2.@@Bhatt DL, Pollack CV, Weitz JI, Jennings LK, Xu S, Arnold SE, Umstead BR, Mays MC, Lee JS: Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers. N Engl J Med. 2019 May 9;380(19):1825-1833. doi: 10.1056/NEJMoa1901778. Epub 2019 Mar 17. |
| Groups | Approved |
| Direct Classification | Triazolopyrimidines |
| SMILES | CCCSC1=NC2=C(N=NN2[C@@H]2C[C@H](OCCO)[C@@H](O)[C@H]2O)C(N[C@@H]2C[C@H]2C2=CC(F)=C(F)C=C2)=N1 |
| Pathways | |
| PharmGKB | PA165374673 |
| ChEMBL | CHEMBL398435 |
