Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10032751HBVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS20002957HPVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS20031069HPVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS20030899HPVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44021579HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44024241HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44014377HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44029002HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TCGA Plot Options
Drug Information
GeneGABRA3
DrugBank IDDB00395
Drug NameCarisoprodol
Target IDBE0000523
UniProt IDP34903
Regulation Typemodulator
PubMed IDs26872987; 28642232
CitationsKumar M, Dillon GH: Assessment of direct gating and allosteric modulatory effects of meprobamate in recombinant GABA(A) receptors. Eur J Pharmacol. 2016 Mar 15;775:149-58. doi: 10.1016/j.ejphar.2016.02.031. Epub 2016 Feb 9.@@Kumar M, Kumar M, Freund JM, Dillon GH: A Single Amino Acid Residue at Transmembrane Domain 4 of the alpha Subunit Influences Carisoprodol Direct Gating Efficacy at GABAA Receptors. J Pharmacol Exp Ther. 2017 Sep;362(3):395-404. doi: 10.1124/jpet.117.242156. Epub 2017 Jun 22.
GroupsApproved
Direct ClassificationCarbamate esters
SMILESCCCC(C)(COC(N)=O)COC(=O)NC(C)C
Pathways
PharmGKBPA448809
ChEMBLCHEMBL1233