| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10032751 | HBV | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS20002957 | HPV | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS20031069 | HPV | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS20030899 | HPV | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS44021579 | HTLV-1 | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS44024241 | HTLV-1 | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS44014377 | HTLV-1 | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
| TVIS44029002 | HTLV-1 | ENSG00000011677.13 | protein_coding | GABRA3 | No | No | 2556 | P34903 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GABRA3 |
|---|---|
| DrugBank ID | DB00425 |
| Drug Name | Zolpidem |
| Target ID | BE0000523 |
| UniProt ID | P34903 |
| Regulation Type | agonist |
| PubMed IDs | 2157817; 11306694; 19345234; 11090095; 21353710 |
| Citations | Pritchett DB, Seeburg PH: Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology. J Neurochem. 1990 May;54(5):1802-4.@@Smith AJ, Alder L, Silk J, Adkins C, Fletcher AE, Scales T, Kerby J, Marshall G, Wafford KA, McKernan RM, Atack JR: Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux. Mol Pharmacol. 2001 May;59(5):1108-18.@@Vlainic J, Pericic D: Effects of acute and repeated zolpidem treatment on pentylenetetrazole-induced seizure threshold and on locomotor activity: comparison with diazepam. Neuropharmacology. 2009 Jun;56(8):1124-30. doi: 10.1016/j.neuropharm.2009.03.010. Epub 2009 Apr 1.@@Crestani F, Martin JR, Mohler H, Rudolph U: Mechanism of action of the hypnotic zolpidem in vivo. Br J Pharmacol. 2000 Dec;131(7):1251-4. doi: 10.1038/sj.bjp.0703717.@@Tan KR, Rudolph U, Luscher C: Hooked on benzodiazepines: GABAA receptor subtypes and addiction. Trends Neurosci. 2011 Apr;34(4):188-97. doi: 10.1016/j.tins.2011.01.004. Epub 2011 Feb 25. |
| Groups | Approved |
| Direct Classification | Phenylimidazoles |
| SMILES | CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C1=CC=C(C)C=C1 |
| Pathways | |
| PharmGKB | PA451976 |
| ChEMBL | CHEMBL911 |
