Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10036449HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS10050122HBVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS30085065HIVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007380HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20007381HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20010779HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20035928HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20057329HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20021555HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TVIS20056904HPVENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB00321
Drug NameAmitriptyline
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs7855217; 39202; 2896792
CitationsCusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65.@@Richelson E: Tricyclic antidepressants and histamine H1 receptors. Mayo Clin Proc. 1979 Oct;54(10):669-74.@@Kachur JF, Allbee WE, Gaginella TS: Antihistaminic and antimuscarinic effects of amitriptyline on guinea pig ileal electrolyte transport and muscle contractility in vitro. J Pharmacol Exp Ther. 1988 May;245(2):455-9.
GroupsApproved
Direct ClassificationDibenzocycloheptenes
SMILESCN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
Pathways
PharmGKBPA448385
ChEMBLCHEMBL629