| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10032906 | HBV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS10040510 | HBV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS10042489 | HBV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30001392 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30001393 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30001394 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30013875 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30088317 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30019456 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
| TVIS30019457 | HIV | ENSG00000162434.14 | protein_coding | JAK1 | Yes | Yes | 3716 | P23458 Q6P669 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | JAK1 |
|---|---|
| DrugBank ID | DB11763 |
| Drug Name | Momelotinib |
| Target ID | BE0004145 |
| UniProt ID | P23458 |
| Regulation Type | inhibitor |
| PubMed IDs | 31450973 |
| Citations | Xu L, Feng J, Gao G, Tang H: Momelotinib for the treatment of myelofibrosis. Expert Opin Pharmacother. 2019 Nov;20(16):1943-1951. doi: 10.1080/14656566.2019.1657093. Epub 2019 Aug 26. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylpyrimidines |
| SMILES | O=C(NCC#N)C1=CC=C(C=C1)C1=CC=NC(NC2=CC=C(C=C2)N2CCOCC2)=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1078178 |
