| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10045810 | HBV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30006137 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30019074 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30077286 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30079341 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS20045047 | HPV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS44017496 | HTLV-1 | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | VDR |
|---|---|
| DrugBank ID | DB00910 |
| Drug Name | Paricalcitol |
| Target ID | BE0000779 |
| UniProt ID | P11473 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 16076355; 19494617; 20204178; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Andress DL: Vitamin D treatment in chronic kidney disease. Semin Dial. 2005 Jul-Aug;18(4):315-21.@@Brancaccio D, Cozzolino M, Pasho S, Fallabrino G, Olivi L, Gallieni M: New acquisitions in therapy of secondary hyperparathyroidism in chronic kidney disease and peritoneal dialysis patients: role of vitamin D receptor activators. Contrib Nephrol. 2009;163:219-26. doi: 10.1159/000223802. Epub 2009 Jun 3.@@Wu-Wong JR, Nakane M, Gagne GD, Brooks KA, Noonan WT: Comparison of the pharmacological effects of paricalcitol and doxercalciferol on the factors involved in mineral homeostasis. Int J Endocrinol. 2010;2010:621687. doi: 10.1155/2010/621687. Epub 2010 Mar 2.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Vitamin D and derivatives |
| SMILES | [H][C@@]1(CC[C@@]2([H])C(CCC[C@]12C)=CC=C1C[C@@H](O)C[C@H](O)C1)[C@H](C)C=C[C@H](C)C(C)(C)O |
| Pathways | |
| PharmGKB | PA450798 |
| ChEMBL | CHEMBL1200622 |
