| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10045810 | HBV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30006137 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30019074 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30077286 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS30079341 | HIV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS20045047 | HPV | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
| TVIS44017496 | HTLV-1 | ENSG00000111424.12 | protein_coding | VDR | No | No | 7421 | P11473 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | VDR |
|---|---|
| DrugBank ID | DB01070 |
| Drug Name | Dihydrotachysterol |
| Target ID | BE0000779 |
| UniProt ID | P11473 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 8380156; 1336906; 20525913; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Qaw F, Calverley MJ, Schroeder NJ, Trafford DJ, Makin HL, Jones G: In vivo metabolism of the vitamin D analog, dihydrotachysterol. Evidence for formation of 1 alpha,25- and 1 beta,25-dihydroxy-dihydrotachysterol metabolites and studies of their biological activity. J Biol Chem. 1993 Jan 5;268(1):282-92.@@Qaw FS, Makin HL, Jones G: Metabolism of 25-hydroxydihydrotachysterol3 in bone cells in vitro. Steroids. 1992 May;57(5):236-43.@@Gallagher JC, Sai AJ: Vitamin D insufficiency, deficiency, and bone health. J Clin Endocrinol Metab. 2010 Jun;95(6):2630-3. doi: 10.1210/jc.2010-0918.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Vitamin D and derivatives |
| SMILES | CC(C)[C@@H](C)C=C[C@@H](C)[C@@]1([H])CC[C@@]2([H])C(CCC[C@]12C)=CC=C1/C[C@@H](O)CC[C@@H]1C |
| Pathways | |
| PharmGKB | PA164744345 |
| ChEMBL | CHEMBL2356023 |
